MBI Logo

Workshop 4: Signal Transduction II: Muscle and Synapse (March 8-12, 2004)

Organizer: James Sneyd and Ed Pate

Communication from cell to cell, or from a neuron to a muscle, is obviously an important physiological process, and one in which calcium plays a crucial role at many points. The release of neurotransmitter at a synapse or neuromuscular junction depends upon a raised calcium concentration in the nerve terminal, while muscle contraction depends on the release of calcium from the sarcoplasmic reticulum leading to contraction of the actin and myosin filaments. Mathematical models have been a part of the long history of the study of both muscles and synapses, with the earliest models being over a century old. In this workshop, we shall begin by studying mathematical models for synapses, and how calcium plays an important role in the secretion of neruotransmitter. We will then continue by considering models of the release of calcium via ryanodine receptors and, finally, consider models of force generation by actin and myosin.

Schedule

Monday, March 8
9:00-9:15AM Welcome and introduction by Avner Friedman, James Sneyd, and Ed Pate
9:15-10:00AM Donald Bers
10:00-10:45AM Coffee break
10:45-11:30AM Christian Soeller
11:30-12:30PM Short talks
12:30-2:00PM Lunch break
2:00-2:45PM Jeremy Rice
2:45-3:15PM Coffee break
3:15-4:00PM Josh Baker
4:00-5:00PM Short talks
5:00-8:00PM MBI Reception and poster
Tuesday, March 9
9:00-9:45AM Saleet Jafri
9:45-10:15AM Coffee break
10:15-11:00AM Julio Vergara
11:00-11:20AM Bill Gibson
11:20-2:00PM Lunch break
2:00-2:45PM Alexandra Zharadnikova
2:45-3:15PM Coffee break
3:15-4:00PM Tim Elston
4:00-4:20PM Tom Shannon
Wednesday, March 10
9:00-9:45AM Mark Cannell
9:45-10:15AM Coffee break
10:15-11:00AM Sasha Panfilov
11:00-11:20PM Jose Puglisi
11:20-2:00PM Lunch break
2:00-2:45PM Nicholas Smith
2:45-3:15PM Coffee break
3:15-4:00PM Earl Homsher
4:00-4:20PM James Keener
Thursday, March 11
9:00-9:45AM Roger Cooke
9:45-10:15AM Coffee break
10:15-10:35AM Daniel Bentil
10:35-10:55AM Steve Lehman
10:55-2:00PM Lunch break
2:00-2:45PM Ed Pate
2:45-3:15PM Coffee break
3:15-4:00PM Hong Qian
4:00-4:20PM Bryant Chase
6:00-9:00PM Buffet Dinner at the Holiday Inn and Magic Show
Friday, March 12
9:00-9:45AM Elise Stanley
9:45-10:15AM Coffee break
10:15-11:00AM Richard Bertram
11:00-11:45AM Victor Matveev