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Current Topics Workshop: The Problems of Phylogenetic Analysis of Large Datasets (December 1-2, 2005)

(Cosponsored by the College of Medicine at The Ohio State University)

Organizers: Daniel Janies, Diego Pol, John Wenzel, Dennis Pearl, and Ward Wheeler

In this workshop, we will focus on recent advances in phylogenetic analysis of large datasets considering two major aspects. The first is the problem of analysis of datasets with a large number of taxa (exceeding several hundreds). This includes recent improvements in tree search algorithms and synergistic application of parallelization strategies using Beowulf clusters and distributed computing. The workshop participants will also compare and discuss the use of improved search tools for competing methods (e.g., parsimony, maximum likelihood, Bayesian). This discussion will illustrate advantages and problems associated specific to various methods with the analysis of datasets with large number of taxa.

The second point of discussion will be the problems associated with analysis of large comparative genomic datasets with various types of information (homology, rearrangement, origin, loss, and multiplication among loci between ancestor and descendant genomes). This problem includes the generalization of edit cost models to account for of multiple kinds of genomic change rather than only DNA substitution.

In summary, this workshop aims to gather leading researchers in this field to discuss common and specific problems, applications, and new models for large-scale phylogenetic and genomic analysis.

Schedule

Thursday, December 1
8:30-9:00am Coffee and Registration
9:00-9:15am Welcome and Introduction by Avner Friedman
9:15-10:00am Walter Fitch: Inferring migration from phylogenies
10:00-10:30am Coffee break
10:30-11:15am Diego Pol: Strategies for Parallelizing of Heuristic Tree Searches Using Parsimony
11:15-11:45am Coffee break
11:45-12:30pm Dan Janies: Applications of large-scale phylogenetic analysis for research in emerging infectious disease
12:30-2:00pm Lunch break
2:00-2:45pm Usman Roshan: Co-evolution of DCMs and base-methods for phylogeny reconstruction
2:45-3:15pm Coffee break
3:15-4:00pm Pablo Goloboff: On divide and conquer strategies for parsimony analysis of large data sets
4:00-4:30pm Coffee break
4:30-5:15pm James Farris
6:00-9:00pm Banquet Dinner at the Holiday Inn
Friday, December 2
9:00-9:45am Bernard Moret: Large-scale phylogenetic reconstruction, the Tree of Life, and CIPRES
9:45-10:15am Coffee break
10:15-11:00am Andres Varon: Minimum Description Length Phylogenetic Analysis
11:00-11:30am Coffee break
11:30-12:15pm Ward Wheeler: Kolmogorov Complexity, Links with Parsimony and Likelihood, and Tests of Methods and Monophyly
12:15-1:45pm Lunch break
1:45-2:30pm Gonzalo Giribet: What is large? Analyzing sets of unaligned sequence data
2:30-3:00pm Coffee break
3:00-3:45pm Alexandros Stamatakis: Computing Huge Trees with Maximum Likelihood: An HPC Perspective
3:45-4:15pm Coffee break
4:15-5:00pm Bret Larget: Bayesian MCMC Approaches for large gene-order phylogenies
5:00-8:00pm Reception in MW 724