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Systems Physiology
September 2006– August 2007
All talks will take place in the MBI Lecture
Hall (Math Building Room 240) unless noted otherwise.
Apply for workshop or tutorial
Workshops Page
Tutorial on the Heart:
September 18-20, 2006
Participants
Tutorial on the Lung: October 18, 2006
Wednesday, 10/18:
The Lung and the Respiratory (Structure, Oxygen Transport) |
| 9:00-10:00am |
Jason Bates |
| 10:30-11:30am |
Jason Bates |
| 1:30-2:30pm |
Jason Bates |
| Presentation materials: PPT1, PPT2, PPT3, PPT4, PPT5 |
Tutorial on Microcirculation:
January 19, 2007
Participants
Tutorial on RAxML: March 5-9, 2007
| Wednesday, 3/7: |
| 10:00-12:00pm |
Alexandros Stamatakis: Using RAxML (hands on tutorial) |
| Presentation materials: PDF |
Tutorial for Workshop 7: Cellular and Organism Models for Glucose Homeostasis and Diabetes
May 18, 2007
Organizers: Richard Bertram and Arthur Sherman
We will review of the biological background on insulin secretion and insulin action and their relation to Type 2 Diabetes, highlighting past successes and current issues. Models for electrical activity of pancreatic beta-cells (ion channels/calcium stores/metabolism), insulin signaling (receptor kinetics/signaling cascades), and whole-body glucose homeostasis (compartmental models/diagnostic tools for beta-cell function and insulin resistance) will be discussed.
Friday, 5/18: |
| 9:00-10:00am |
Electrophysiology of Pancreatic Islets - Richard Bertram
Topics: relaxation oscillators and classical bursting, fast-slow decomposition, role of the ER, phantom bursting, modulation by G-protein signaling, electrical coupling |
| 10:00-11:00pm |
Break and informal discussion |
| 11:00-12:00pm |
Glucose Metabolism in the Beta-Cell - Richard Bertram
Topics: glycolysis, citric acid cycle, oxidative phosphorylation, models for metabolic oscillations |
| 12:00-1:00pm |
Lunch break |
| 1:00-2:00pm |
Insulin Secretion - Arthur Sherman
Topics: triggering and amplifying pathways, exocytosis, models for secretion, whole-body pulsatility and synchrony |
| 2:00-3:00pm |
Break and informal discussion |
| 3:00-4:00pm |
Whole-Body Metabolism and Disease - Arthur Sherman
Topics: insulin resistance, beta-cell function, beta-cell mass, models for assessing insulin resistance and beta-cell function |
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